Selective Optogenetic Stimulation with MEA to Detect Spread – Papasavvas et al. 2020 eNeuro Interneurons are directly connected by gap junctions to other interneurons, and this provides a [...]
Targeted Illumination in Zebrafish – Tabor et al. 2018 Current Biology Tabor et al. 2018 examined the cellular-basis of sensory filtering in zebrafish using prepulse inhibition (PPI). PPI [...]
The ability to illuminate select neurons within a population of optogenetic-expressing neurons is called cellular-resolution optogenetics (Shemesh et al. 2017). To use this technique, researchers [...]
Patterned illumination technologies enable researchers to selectively illuminate parts of their sample for optogenetic stimulation. One application of this is cellular-resolution optogenetics: [...]
Optogenetics is a technique to manipulate genetically-defined neural activity with light, and it has two main advantages: Millisecond Temporal Precision Genetically-Defined Spatial Precision [...]
Optogenetics unlocks the ability to activate or inhibit select populations of neurons. With this technique, researchers have been able to investigate the causal relationship between neural [...]
For years, neuroscientists have been fixated on understanding how behavior and cognition arise from neural circuit activity. To begin investigating these questions, scientists have been employing [...]
The invention of optogenetics has enabled scientists to use light to turn cell-type specific neural activity on or off with millisecond-precision to probe neural circuit function. Complementing [...]
A long-standing objective in neuroscience has been elucidating how in vivo neural activity relates to sensory processing, behaviour, cognition, and cortical processing. Researchers have attempted [...]
If someone were to describe in vivo calcium imaging to you, it might sound quite simple. When you dig deeper, you start to appreciate the complexity associated with the biology and equipment [...]
