Overview
Fiber Photometry is a form of calcium imaging in which gross neural activity levels are measured from select populations of neurons across time.
For more details, please click “Fiber Photometry: The Ultimate Guide” here➡️
Key System Requirements
- Easy-to-use hardware and software interfaces
- Simultaneous collection from multiple regions of interest
- Robust tools for data synchronization with peripheral devices
- Low impact mount to reduce animal strain
- Multi-color configuration for isosbestic signal collecting and multi-sensor probing
- High temporal resolution data collection
- Simple integration with optogenetic tools
- Real-time signal visualization
OASIS Implant System
- Compatible with any C-mount scientific camera
- Capable of collecting data from multiple ROIs, and/or multiple animals
- Synchronization and time-stamping across all hardware devices in the system
- Modular design, can be easily integrated with optogenetic tools
- Upgradable to cellular-resolution calcium imaging
Research Highlights using OASIS Implant
(Pharmaceutics 2022).
The cingulate cortex (CC) is a key brain region in the limbic system that coordinates actions and motivational behaviors. Somatostatin-expressing GABAergic neurons in the cingulate cortex (CCSST) can provide powerful inhibition to the CC circuitry through high basal firing activity and synchronized firing.
The video shows Ca2+ activity of somatostation-expressing cingulate cortex neurons during social interaction collected using the Mightex OASIS Implant system.
For more details, please click here!
Huanhuan Li & Prof. Geoffrey Lau
City University of Hong Kong, Hong Kong
