With nearly 700 customers worldwide and over 130 scientific publications, Mightex’s Polygon is leading the market and sets the gold standard in patterned illumination. It has enabled scientists to conduct cutting-edge research on a wide range of frontiers such as neuroscience optogenetics, cell biology optogenetics, photoactivation & photoconversion, photopatterning, light-directed spatiotemporal omics, and microfluidics, etc.
Below is a list of customer success examples:
Serotonergic modulation of vigilance states in zebrafish and mice, Nature Communications, 15(1), 2596, (2024).
Yang Zhao & Prof. Jianren Song
Tongji University, Medical School, China
Neuronal sensorimotor integration guiding salt concentration navigation in Caenorhabditis elegans, Proceedings of the National Academy of Sciences (2024).
Ayaka Matsumoto & Prof. Yuichi Iino
The University of Tokyo, Japan
Bingzhi Wu & Prof. Sambeeta Das
University of Delaware, USA
All-optical interrogation of millimeter-scale networks and application to developing ferret cortex, Journal of Neuroscience Methods 403, 110051 (2024).
Haleigh N. Mulholland & Prof. Gordon B. Smith
University of Minnesota, USA
Dr. Mai-Anh T. Vu & Prof. Mark W. Howe
Boston University, USA
Michael B. Sheets & Prof. Mary J. Dunlop
Boston University, USA
Published on 2023/11/07
Dr. Mizuki Honda & Prof. Yasuyuki Ohkawa
Kyoto University, Japan
Abdulkadir Mohamed & Prof. Liria Masuda-Nakagawa
The University of Cambridge, UK
Deep model predictive control via optogenetics with the Mightex Polygon, Boston University, (2023). 1st prize.
Dr. Jean-Baptiste Lugagne & Prof. Mary Dunlop
Boston University, USA
Discovering a new cardiac arrhythmia mechanism in neonatal rat atrial monolayers using patterned illumination, Laboratory of Experimental Cardiology, Leiden University Medical Center, (2023). 2nd prize.
Dr. Tim De Coster & Prof. Daniël A. Pijnappels
Leiden University Medical Center, The Netherlands
Exploration of the mechanism of refractive error in the mouse retina, The Hong Kong Polytechnic University, (2023). 3rd prize.
Dr. So Chung Him & Prof. Pan Feng
The Hong Kong Polytechnic University, Hong Kong
Interleaved complementary dual-λ photo-stimulation facilitates high spatial-temporal precision labeling, Sichuan University, (2023). 3rd prize.
Xinyu Xie & Prof. Zhipeng Yu
Sichuan University, China
Induction of CA1 Theta-Nested Gamma Oscillations Using Layer-Specific Optogenetic Stimulation, University of Cambridge, (2021).
Dr. James L. Butler & Prof. Ole Paulsen MD
University of Cambridge, UK
Visualizing Vimentin Filament Dynamics Using Photoconversion with the Mightex Polygon, Northwestern University, (2023).
Dr. Bhuvanasundar Renganathan & Prof. Vladimir I Gelfand
Northwestern University, USA
Short-term plasticity in hippocampal CA1 synapses for different presynaptic activity patterns. Effect of in vivo like background activity on long-term synaptic plasticity, Bhalla Lab, National Centre For Biological Sciences, (2023).
Dr. Sulu Mohan & Prof. Upinder S. Bhalla
National Centre for Biological Sciences, India
Relating cerebellar glutamatergic dysfunction and age effects on behavioral phenotype in Shank3△e4-22 mutant mice, (SFN 2023).
Rajaram Kshetri & Prof. Ben Richardson
Southern Illinois University, USA
Dr. Mohamed Elsayed & Prof. Aaron Wheeler
University of Toronto, Canada
Light-Seq: light-directed in situ barcoding of biomolecules in fixed cells and tissues for spatially indexed sequencing , Nature Methods19(11), 1393-1402 (2022).
Dr. Jocelyn Y. Kishi & Prof. Peng Yin
Harvard Medical School, Boston, MA, USA
Mark Mittmoen & Prof. Ofer Kedem
Kedem Group, Marquette University, USA
Restoration of Visual Function and Cortical Connectivity After Ischemic Injury Through NeuroD1-Mediated Gene Therapy, Frontiers in Cell and Developmental Biology, 9, 720078, (2021).
Dr. Yu Tang & Prof. Alexander Chubykin
Purdue University, USA
High-depth spatial transcriptome analysis by photo-isolation chemistry, Nature Communications 12(1), 4416 (2021).
Dr. Mizuki Honda & Prof. Yasuyuki Ohkawa
Kyoto University, Japan
![](https://www.mightexbio.com/wp-content/uploads/2023/12/toettcher2-150x150.jpg")
Protein Phase Separation Provides Long-Term Memory of Transient Spatial Stimuli, Princeton University, (2021).
Dr. Elliot Dine, MD & Prof. Jared Toettcher
Princeton University, USA
Cortical Observation by Synchronous Multifocal Optical Sampling Reveals Widespread Population Encoding of Actions, Stanford University, (2021).
Dr. Isaac Kauvar & Prof. Karl Deisseroth
Stanford University, USA
Optogenetic characterization of muscular responses in the tibialis anterior (TA) muscle, Marquette University and the Medical College of Wisconsin, (2021).
Dr. Emma Moravec & Prof. Jordan Williams
Marquette University, USA
Optogenetic stimulation of olfactory cortex to mimic odors, New York University, (2021).
Dr. Pedro Herrero-Vidal & Prof. Dima Rinberg
New York University, USA
Examining functional connectivity within the cerebellar microcircuit, McGill University, (2021).
Dr. Kim Gruver & Prof. Alanna Watt
McGill University, USA
Pixelated wrinkles using patterned optical phase retardation, Chungnam National University of Korea, (2021).
Dr. Kitae Kim & Prof. Jun-Hee Na
Chungnam National University, Korea
Photopatterning of multi-domain DNA hydrogels, Johns Hopkins University, (2021).
Dr. Misha Rubanov & Prof. Rebecca Schulman
Johns Hopkins University, USA
A rostro-caudal map of V1 inhibition in axial motor circuits, Washington University in St Louis, (2021).
Dr. Mohini Sengupta & Prof. Martha Bagnall
Washington University in St Louis, USA
Dr. Archana Proddutur & Prof. Viji Santhakumar
University of California Riverside, USA
Optoelectronic tweezers based on patterned illumination for cell and micro-robotic manipulation, (μTAS 2019).
Dr. Shuailong Zhang & Prof. Aaron Wheeler
University of Toronto, Canada
Dr. Kim Gruver & Prof. Alanna J Watt
McGill University, USA
Dr. Azam Asgarihafshejani & Prof. Jean-Claude Lacaille
University of Montreal, Canada
Dr. Jeffrey van Haren & Prof. Torsten Wittmann
UCSF, USA
Dr. Matthew Tran & Prof. Blake Richards
University of Toronto, Canada
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Bingzhi Wu & Prof. PhD Sambeeta Das
University of Delaware, USA
Dr. Mizuki Honda & Prof. Yasuyuki Ohkawa
Kyoto University, Japan
